Background One of the most common causes of postoperative morbidity is postoperative surgical site infection (SSI). Healthcare-associated infection is a subject of great concern in healthcare services. The goal of the present study is to estimate the relative effectiveness of skin preparation solution chlorhexidine scrub followed by povidone-iodine painting in the prevention of SSIs after caesarean delivery and abdominal gynecological surgery. Material and Methods This is a 1-year randomized prospective research done at a tertiary care institution in western Rajasthan. Women who underwent caesarean and gynecological operations were randomly assigned to one of two groups. Enrolled patients were randomly assigned to have the surgical site painted with 10% povidone-iodine or a chlorhexidine-alcohol preparatory scrub followed by povidone-iodine paint. According to the Centres for Disease Control and Prevention criteria, the outcomes were any SSI occurring within a week or during the 30-day follow-up period following the operation, including any superficial or deep SSI. Results A total of 251 patients were randomly assigned to two groups. Group A (povidone-iodine paint) received 121 patients, whereas Group B (chlorhexidine scrub + povidone-iodine paint) received 129 cases. The overall SSI rate in the present study was 8.76%. The SSI rate was lower in Group B (chlorhexidine scrub + povidone-iodine paint) as compared to Group A (povidone-iodine paint only) (5.4% vs. 12.4%; p = 0.04). Conclusion This study highlighted that chlorhexidine-alcohol scrubbing followed by povidone-iodine painting provides superior skin antisepsis in comparison to povidone-iodine painting alone.
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Boston Univ, VA Boston Healthcare Syst, Harvard Med Sch, Dept Surg, VABHCS 112A,1400 VFW Pkwy, Boston, MA 02132 USABoston Univ, VA Boston Healthcare Syst, Harvard Med Sch, Dept Surg, VABHCS 112A,1400 VFW Pkwy, Boston, MA 02132 USA
Itani, Kamal M. F.
Hawn, Mary T.
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Univ Alabama Birmingham, Dept Surg, Sect Gastrointestinal Surg, Birmingham, AL 35294 USA
Birmingham Vet Adm Hosp, C SMART, Birmingham, AL 35233 USABoston Univ, VA Boston Healthcare Syst, Harvard Med Sch, Dept Surg, VABHCS 112A,1400 VFW Pkwy, Boston, MA 02132 USA
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Thomas Jefferson Univ, Dept Orthoped Surg, Philadelphia, PA 19107 USAUniv Wisconsin, Dept Orthoped & Rehabil, UWMF Centennial Bldg,1685 Highland Ave,6th Floor, Madison, WI 53705 USA
Vaccaro, Alexander R.
Radcliff, Kristen
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Thomas Jefferson Univ, Dept Orthoped Surg, Rothman Inst, Philadelphia, PA 19107 USAUniv Wisconsin, Dept Orthoped & Rehabil, UWMF Centennial Bldg,1685 Highland Ave,6th Floor, Madison, WI 53705 USA
Radcliff, Kristen
Arnold, Paul M.
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Univ Kansas, Med Ctr, Dept Neurosurg, Kansas City, KS 66103 USAUniv Wisconsin, Dept Orthoped & Rehabil, UWMF Centennial Bldg,1685 Highland Ave,6th Floor, Madison, WI 53705 USA
Arnold, Paul M.
Lawrence, Brandon D.
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Univ Utah, Dept Orthopaed, Salt Lake City, UT USAUniv Wisconsin, Dept Orthoped & Rehabil, UWMF Centennial Bldg,1685 Highland Ave,6th Floor, Madison, WI 53705 USA
Lawrence, Brandon D.
Shamji, Mohammed F.
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Univ Toronto, Dept Surg, Div Neurosurg, Toronto, ON, CanadaUniv Wisconsin, Dept Orthoped & Rehabil, UWMF Centennial Bldg,1685 Highland Ave,6th Floor, Madison, WI 53705 USA
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Washington Univ, Sch Med, Dept Surg, Sect Acute & Crit Care Surg, St Louis, MO 63110 USAWashington Univ, Sch Med, Dept Surg, Sect Acute & Crit Care Surg, St Louis, MO 63110 USA
Winfield, Robert D.
Reese, Stacey
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Washington Univ, Sch Med, Dept Surg, Sect Acute & Crit Care Surg, St Louis, MO 63110 USAWashington Univ, Sch Med, Dept Surg, Sect Acute & Crit Care Surg, St Louis, MO 63110 USA
Reese, Stacey
Bochicchio, Kelly
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Washington Univ, Sch Med, Dept Surg, Sect Acute & Crit Care Surg, St Louis, MO 63110 USAWashington Univ, Sch Med, Dept Surg, Sect Acute & Crit Care Surg, St Louis, MO 63110 USA
Bochicchio, Kelly
Mazuski, John E.
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Washington Univ, Sch Med, Dept Surg, Sect Acute & Crit Care Surg, St Louis, MO 63110 USAWashington Univ, Sch Med, Dept Surg, Sect Acute & Crit Care Surg, St Louis, MO 63110 USA
Mazuski, John E.
Bochicchio, Grant V.
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Washington Univ, Sch Med, Dept Surg, Sect Acute & Crit Care Surg, St Louis, MO 63110 USAWashington Univ, Sch Med, Dept Surg, Sect Acute & Crit Care Surg, St Louis, MO 63110 USA