Bioadhesive giant vesicles for monitoring hydroperoxidation in lipid membranes

被引:24
|
作者
Aoki, P. H. B. [1 ,2 ,3 ]
Schroder, A. P. [1 ]
Constantino, C. J. L. [2 ]
Marques, C. M. [1 ]
机构
[1] Univ Strasbourg, CNRS, Inst Charles Sadron, UP 22, F-67034 Strasbourg 2, France
[2] Univ Estadual Paulista, Fac Ciencias & Tecnol, BR-19060900 Presidente Prudente, SP, Brazil
[3] Univ Sao Paulo, Sao Carlos Inst Phys, BR-13560970 Sao Carlos, SP, Brazil
基金
巴西圣保罗研究基金会;
关键词
PEROXIDATION; OXIDATION; BILAYERS;
D O I
10.1039/c5sm01019e
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
Osmotic stresses, protein insertion or lipid oxidation lead to area increase of self-assembled lipid membranes. However, methods to measure membrane expansion are scarce. Challenged by recent progress on the control of phospholipid hydroperoxidation, we introduce a method to quantitatively evaluate membrane area increase based on the bio-adhesion of Giant Unilamellar Vesicles.
引用
收藏
页码:5995 / 5998
页数:4
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