Two Novel Diphenolic Metabolites from the Inedible Mushroom Thelephora palmata

被引:0
|
作者
Nishio, Ayako [1 ]
Mikami, Haruka [1 ]
Imagawa, Hiroshi [1 ]
Hashimoto, Toshihiro [1 ]
Tanaka, Masami [1 ]
Ito, Takuya [2 ]
Iguchi, Miki [1 ]
Iseki, Kanako [1 ]
Noji, Masaaki [1 ]
Umeyama, Akemi [1 ]
机构
[1] Tokushima Bunri Univ, Fac Pharmaceut Sci, Tokushima 7708514, Japan
[2] Toyama Univ, Inst Nat Med, Toyama 9300194, Japan
关键词
Thelephora palmata; Diphenolic metabolite; Thelepalmatin; Antimicrobial activity; Bacillus subtilis; Staphylococcus aureus; ANTITRYPANOSOMAL ACTIVITY; FRUITING BODIES; DERIVATIVES;
D O I
暂无
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
During the search for bioactive secondary metabolites, thelepalmatins A and B (1 and 2) were isolated from the fresh fruiting bodies of Thelephora palmata, together with four known compounds (3-6). Their structures were elucidated using MS analyses, and extensive 2D-heteronuclear NMR data interpretation. Compounds 3, 4 and 6 showed antimicrobial activities against Staphylococcus aureus and Bacillus subtilis with MIC values of 21.7-70.4 mu M.
引用
收藏
页码:1147 / 1149
页数:3
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