Two Novel Diphenolic Metabolites from the Inedible Mushroom Thelephora palmata

被引:0
|
作者
Nishio, Ayako [1 ]
Mikami, Haruka [1 ]
Imagawa, Hiroshi [1 ]
Hashimoto, Toshihiro [1 ]
Tanaka, Masami [1 ]
Ito, Takuya [2 ]
Iguchi, Miki [1 ]
Iseki, Kanako [1 ]
Noji, Masaaki [1 ]
Umeyama, Akemi [1 ]
机构
[1] Tokushima Bunri Univ, Fac Pharmaceut Sci, Tokushima 7708514, Japan
[2] Toyama Univ, Inst Nat Med, Toyama 9300194, Japan
关键词
Thelephora palmata; Diphenolic metabolite; Thelepalmatin; Antimicrobial activity; Bacillus subtilis; Staphylococcus aureus; ANTITRYPANOSOMAL ACTIVITY; FRUITING BODIES; DERIVATIVES;
D O I
暂无
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
During the search for bioactive secondary metabolites, thelepalmatins A and B (1 and 2) were isolated from the fresh fruiting bodies of Thelephora palmata, together with four known compounds (3-6). Their structures were elucidated using MS analyses, and extensive 2D-heteronuclear NMR data interpretation. Compounds 3, 4 and 6 showed antimicrobial activities against Staphylococcus aureus and Bacillus subtilis with MIC values of 21.7-70.4 mu M.
引用
收藏
页码:1147 / 1149
页数:3
相关论文
共 50 条
  • [1] Pregnane-type steroids from the inedible mushroom Thelephora terrestris
    Radulovic, N
    Quang, DN
    Hashimoto, T
    Nukada, M
    Tanaka, T
    Asakawau, Y
    CHEMICAL & PHARMACEUTICAL BULLETIN, 2005, 53 (03) : 309 - 312
  • [2] Terrestrins A-G:: p-Terphenyl derivatives from the inedible mushroom Thelephora terrestris
    Radulovic, N
    Quang, DN
    Hashimoto, T
    Nukada, M
    Asakawa, Y
    PHYTOCHEMISTRY, 2005, 66 (09) : 1052 - 1059
  • [3] Thelephantins D-H:: five p-terphenyl derivatives from the inedible mushroom Thelephora aurantiotincta
    Quang, DN
    Hashimoto, T
    Hitaka, Y
    Tanaka, M
    Nukada, M
    Yamamoto, I
    Asakawa, Y
    PHYTOCHEMISTRY, 2003, 63 (08) : 919 - 924
  • [4] Thelephantins A, B and C:: three benzoyl p-terphenyl derivatives from the inedible mushroom Thelephora aurantiotincta
    Quang, DN
    Hashimoto, T
    Nukada, M
    Yamamoto, I
    Hitaka, Y
    Tanaka, M
    Asakawa, Y
    PHYTOCHEMISTRY, 2003, 62 (01) : 109 - 113
  • [5] Purification, characterization, and bioactivity of two new polysaccharide fractions from Thelephora ganbajun mushroom
    Gong, Li-Li
    Meng, Fan-Ju
    Hou, Yu-Chen
    Liu, Yu
    Xu, Jia-Jia
    Zhang, Wen-Na
    Chen, Yan
    JOURNAL OF FOOD BIOCHEMISTRY, 2020, 44 (01)
  • [6] Vialinins A and B: Novel bioactive compounds from Thelephora vialis, an edible mushroom in China
    Xie, Chun
    Abe, Naoki
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2006, 232 : 122 - 122
  • [7] Purification of a novel ribonuclease from dried fruiting bodies of the edible wild mushroom Thelephora ganbajun
    Wang, HX
    Ng, TB
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2004, 324 (02) : 855 - 859
  • [8] New azaphilones from the inedible mushroom Hypoxylon rubiginosum
    Quang, DN
    Hashimoto, T
    Stadler, M
    Asakawa, Y
    JOURNAL OF NATURAL PRODUCTS, 2004, 67 (07): : 1152 - 1155
  • [9] Lanostane triterpenoids from the inedible mushroom Fomitopsis spraguei
    Quang, DN
    Arakawa, Y
    Hashimoto, T
    Asakawa, Y
    PHYTOCHEMISTRY, 2005, 66 (14) : 1656 - 1661
  • [10] Thelephorin A:: a new radical scavenger from the mushroom Thelephora vialis
    Tsukamoto, S
    Macabalang, AD
    Abe, T
    Hirota, H
    Ohta, T
    TETRAHEDRON, 2002, 58 (06) : 1103 - 1105