Expanding the membrane-protein NMR toolkit

被引：2
|
作者：
Cheng, Ricky C. [1 ]
Maduke, Merritt [1 ]
机构：
[1] Stanford Univ, Sch Med, Dept Mol & Cellular Physiol, Stanford, CA 94305 USA
来源：
NATURE CHEMICAL BIOLOGY | 2020年 / 16卷 / 09期
关键词：
D O I：
10.1038/s41589-020-0597-7
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
An NMR method to monitor conformational states of challenging large protein targets is described. The method, which can be used to evaluate distances between two labels and to measure conformational exchange rates, revealed an unanticipated outward-facing state in a glutamate transporter.
引用
收藏
页码：937 / 938
页数：3
相关论文
共 50 条
  • [31] MEMBRANE-PROTEIN ASSEMBLY - RULES OF THE GAME
    VONHEIJNE, G
    BIOESSAYS, 1995, 17 (01) : 25 - 30
  • [32] CURRENT CONCEPTS IN MEMBRANE-PROTEIN RECONSTITUTION
    MADDEN, TD
    CHEMISTRY AND PHYSICS OF LIPIDS, 1986, 40 (2-4) : 207 - 222
  • [33] TOWARDS THE STRUCTURE OF THE MEMBRANE-PROTEIN, RHODOPSIN
    YEAGLE, PL
    ALDERFER, JL
    ALBERT, AD
    JOURNAL OF CELLULAR BIOCHEMISTRY, 1995, : 78 - 78
  • [34] Membrane-protein crystals for neutron diffraction
    Sorensen, Thomas Lykke-Moller
    Hjorth-Jensen, Samuel John
    Oksanen, Esko
    Andersen, Jacob Lauwring
    Olesen, Claus
    Moller, Jesper Vuust
    Nissen, Poul
    ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY, 2018, 74 : 1208 - 1218
  • [35] Cryoem Studies of Membrane-Protein Interactions
    Mizuno, Naoko
    BIOPHYSICAL JOURNAL, 2013, 104 (02) : 206A - 207A
  • [36] A Fluorinated Detergent for Membrane-Protein Applications
    Frotscher, Erik
    Danielczak, Bartholomaeus
    Vargas, Carolyn
    Meister, Annette
    Durand, Grgory
    Keller, Sandro
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2015, 54 (17) : 5069 - 5073
  • [37] Membrane-protein biosynthesis at the endoplasmic reticulum
    High, S
    Greenfield, JJA
    Meacock, SL
    Oliver, JD
    BIOCHEMICAL SOCIETY TRANSACTIONS, 1999, 27 : 883 - 888
  • [38] PHOTODAMAGE AND REPAIR OF A THYLAKOID MEMBRANE-PROTEIN
    TAKAHASHI, M
    NIPPON NOGEIKAGAKU KAISHI-JOURNAL OF THE JAPAN SOCIETY FOR BIOSCIENCE BIOTECHNOLOGY AND AGROCHEMISTRY, 1988, 62 (07): : 1108 - 1111
  • [39] A STUDY OF PHOSPHORYLATION OF THE MEASLES MEMBRANE-PROTEIN
    RIMA, BK
    LAPPIN, SA
    ROBERTS, MW
    MARTIN, SJ
    JOURNAL OF GENERAL VIROLOGY, 1981, 56 (OCT): : 447 - 450
  • [40] INTERMEDIATES IN THE FOLDING OF THE MEMBRANE-PROTEIN BACTERIORHODOPSIN
    BOOTH, PJ
    FLITSCH, SL
    STERN, LJ
    GREENHALGH, DA
    KIM, PS
    KHORANA, HG
    NATURE STRUCTURAL BIOLOGY, 1995, 2 (02): : 139 - 143
12345