A stereocontrolled synthetic route to anti-β-amino alcohols

被引：9
|
作者：
Kang, SH [1 ]
Hwang, YS
Youn, JH
机构：
[1] Korea Adv Inst Sci & Technol, Sch Mol Sci BK21, Dept Chem, Taejon 305701, South Korea
[2] Sun Moon Univ, Dept Chem Engn, Chungnam 336840, South Korea
来源：
TETRAHEDRON LETTERS | 2001年 / 42卷 / 43期
关键词：
D O I：
10.1016/S0040-4039(01)01611-2
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A physiologically indispensable beta -amino hydroxy functionality has been constructed with complete anti-stereoselectivity by intramolecular iodoamidation of (Z)-olefinic homoallylic trichloroacetimidates 4-6, 18, 20, 30 and 32, which comprise bulky substituents at the vinylic positions. (C) 2001 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：7599 / 7603
页数：5
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