RETRACTED: Protective Properties of the Extract of Chrysanthemum on Patients with Ischemic Stroke (Retracted Article)

被引:6
|
作者
Zhu, Zhuoying [1 ]
Qian, Shuxia [1 ]
Lu, Xudong [1 ]
Xu, Congying [1 ]
Wang, Yanping [1 ]
Zhang, Xiaoling [1 ]
Yu, Xin [2 ]
Shen, Yufei [1 ]
机构
[1] Jiaxing Univ, Affiliated Hosp 2, Inst Neurol, Jiaxing 314000, Peoples R China
[2] Bengbu Med Coll, Bengbu 233000, Peoples R China
关键词
PATHOPHYSIOLOGY; MORIFOLIUM;
D O I
10.1155/2021/3637456
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
Investigation of the protective effect of chrysanthemum extract in ischemic strokes patients is among the challenging issues with the traditional hospital system in general and smart technology-based hospitals in particular. In this study, we have evaluated the protective effect of chrysanthemum extract on patients with ischemic stroke by detecting the severity of stroke, neuronal indexes, and oxidative stress biomarkers. For this purpose, forty-six patients with ischemic stroke were randomly divided into the control group (n = 30) and chrysanthemum group (n = 30). The control group received standard stroke treatment, and the chrysanthemum group was treated with chrysanthemum extract 400 mg/day (200 mg/day, twice/day) on the basis of standard treatment. The groups were compared the effect of saffron capsules using the National Institute of Health Stoke Scale (NIHSS), serum neuron specific enolase (NSE), S100, brain-derived neurotrophic factor (BDNF), malondialdehyde (MDA), Su-peroxide dismutase (SOD), and total antioxidant capacity (TAC) levels, at the time of first day and fourth day after treatment. On the first day after treatment, there was no significant difference in the NIHSS score, serum NSE, S100, BDNF, MDA, SOD, and TAC levels between the chrysanthemum group and the control group (P > 0.05). On the fourth day after treatment, the NIHSS, serum NSE, S100, and MDA levels were significantly reduced in the chrysanthemum group compared to the control group, while the BDNF, SOD, and TAC levels were higher (P < 0.05). In addition, compared to the levels on the first day, the NIHSS, serum NSE, S100, and MDA levels were significantly reduced, and the BDNF, SOD, and TAC levels were increased in the chrysanthemum group on the fourth day (P < 0.05). Chrysanthemum extract has the effects of scavenging oxygen free radicals and antioxidation and has a neuroprotective effect on ischemic stroke patients.
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页数:8
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