Photocleavable molecule for laser desorption ionization mass spectrometry

被引：13
|
作者：
Maki, Toshihide
Ishida, Koji
机构：
[1] Nagasaki Univ, Joint Res Ctr, Nagasaki 8528521, Japan
[2] Nagasaki Univ, Grad Sch Biomed Sci, Nagasaki 8528521, Japan
来源：
JOURNAL OF ORGANIC CHEMISTRY | 2007年 / 72卷 / 17期
关键词：
D O I：
10.1021/jo070621b
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A new photocleavable molecule for laser desorption ionization mass spectrometry (LDI-MS) was designed and synthesized. The molecule exhibited high sensitivity for negative mode MS detection with good chemical stability. The molecule was successfully applied to molecular tag for (LDI-MS). Kinetic measurement of the amidation reaction and monitoring of aminolysis of acetylated sugars were demonstrated with the molecular tag.
引用
收藏
页码：6427 / 6433
页数：7
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