Evaluation of Toxoplasma gondii recombinant antigens for early diagnosis of congenital toxoplasmosis

被引：2

作者：

Rivera, Elias M. ^{[1
]}

Moscatelli, Guillermo ^{[2
,3
]}

Ballering, Griselda ^{[2
]}

Ganuza, Agustina ^{[1
]}

Alonso, Andres M. ^{[1
]}

Moroni, Samanta ^{[2
]}

Clemente, Marina ^{[4
]}

Altcheh, Jaime ^{[2
,3
]}

Angel, Sergio O. ^{[1
]}

机构：

[1] Univ Nacl Gen San Martin UNSAM, CONICET, INTECH, Lab Parasitol Mol, Buenos Aires, DF, Argentina

[2] Hosp Ninos Dr Ricardo Gutierrez, Serv Parasitol & Chagas, Gallo 1330 CI425EFD, Buenos Aires, DF, Argentina

[3] CONICET GCBA, Inst Multidisciplinario Invest Patol Pediat IMIPP, Buenos Aires, DF, Argentina

[4] Univ Nacl Gen San Martin UNSAM, CONICET, INTECH, Lab Biofabr & Vacunas, Buenos Aires, DF, Argentina

来源：

DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE | 2022年 / 102卷 / 03期

关键词：

Toxoplasmosis; Diagnosis; Congenital infection; Recombinant antigen; Serology; PROTEINS; INFANTS;

D O I：

10.1016/j.diagmicrobio.2021.115608

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

The performance of Toxoplasma rGra8, rMic1, and the chimeric rGra4-Gra7 antigens for early congenital toxoplasmosis (CT) diagnosis was evaluated. Sera from CT patients showed high IgG reactivity to rMic1, rGra8, and rGra4-Gra7. The seroreactivity of samples from uninfected infants was lost within 2 months of age. (C) 2021 Published by Elsevier Inc.

引用

页数：3

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