Evaluation of Toxoplasma gondii recombinant antigens for early diagnosis of congenital toxoplasmosis

被引：2
|
作者：
Rivera, Elias M. [1 ]
Moscatelli, Guillermo [2 ,3 ]
Ballering, Griselda [2 ]
Ganuza, Agustina [1 ]
Alonso, Andres M. [1 ]
Moroni, Samanta [2 ]
Clemente, Marina [4 ]
Altcheh, Jaime [2 ,3 ]
Angel, Sergio O. [1 ]
机构：
[1] Univ Nacl Gen San Martin UNSAM, CONICET, INTECH, Lab Parasitol Mol, Buenos Aires, DF, Argentina
[2] Hosp Ninos Dr Ricardo Gutierrez, Serv Parasitol & Chagas, Gallo 1330 CI425EFD, Buenos Aires, DF, Argentina
[3] CONICET GCBA, Inst Multidisciplinario Invest Patol Pediat IMIPP, Buenos Aires, DF, Argentina
[4] Univ Nacl Gen San Martin UNSAM, CONICET, INTECH, Lab Biofabr & Vacunas, Buenos Aires, DF, Argentina
来源：
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE | 2022年 / 102卷 / 03期
关键词：
Toxoplasmosis; Diagnosis; Congenital infection; Recombinant antigen; Serology; PROTEINS; INFANTS;
D O I：
10.1016/j.diagmicrobio.2021.115608
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
The performance of Toxoplasma rGra8, rMic1, and the chimeric rGra4-Gra7 antigens for early congenital toxoplasmosis (CT) diagnosis was evaluated. Sera from CT patients showed high IgG reactivity to rMic1, rGra8, and rGra4-Gra7. The seroreactivity of samples from uninfected infants was lost within 2 months of age. (C) 2021 Published by Elsevier Inc.
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页数：3
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