Multicentric reticulohistiocytosis: report of a case with systemic disease

被引：2
|
作者：
Stock, N
Saikali, S
Chevrant-Breton, J
Leroy, JP
Le Gall, F
机构：
[1] CHU Pontchaillou, Dept Pathol Anat, F-35033 Rennes, France
[2] CHU Pontchaillou, Dermatol Serv, F-35000 Rennes, France
[3] CHU Morvan, Anat Pathol Lab, F-29000 Brest, France
来源：
ANNALES DE PATHOLOGIE | 2005年 / 25卷 / 01期
关键词：
multicentric reticulohistiocytosis; non Langherhans histiocytosis; immunohistochemistry; electron microscopy;
D O I：
10.1016/S0242-6498(05)80099-9
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
Multicentric reticulohistiocytosis (RHM) is a rare non Langherhans cell histiocytosis with skin and joint involvment. Nearly all organs can be involved. Association with cancer occurs in about 25% of cases. Association with auto-immune diseases has also been recorded. Microscopic examination Shows a histiocytic nodular infiltrate made of giant cells with ground-glass appearance and PAS positive cytoplasm. Immunostaining shows cell positivity for CD68 and negativity for CD1a and S100 protein. No Birbeck granules are found at ultrostructural examination.
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收藏
页码：50 / 53
页数：4
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