Synthesis of 2',3'-anhydronucleosides of pyrazolo[3,4-d]pyrimidine as antiviral agents

被引：0
|
作者：
Tripathi, RP
Mishra, A
Pratap, R
Bhakuni, DS
机构：
[1] UNIV LUCKNOW,DEPT CHEM,LUCKNOW 226007,UTTAR PRADESH,INDIA
[2] CENT DRUG RES INST,DIV MED CHEM,LUCKNOW 226001,UTTAR PRADESH,INDIA
来源：
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY | 1996年 / 35卷 / 05期
关键词：
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
4,6-Bismethylthio-N-1-(2',3'-anhydro-beta-D-lyxofuranosyl), and 4,6-bismethylthio-N-2-(2',3'-anhydro-beta-D-ribofuranosyl)-pyrazolo[3,4-d]pyrimidines (10 and 17) have been synthesized by 2',3'transelimination of the corresponding N-1(9)- and N-2(12)-beta-D-xylofuranosylpyrazolo[3,4-d]pyrimidines. The compounds and their intermediates have been screened for their antiviral activities against RDV and EMCV exhibiting 10-100% activity.
引用
收藏
页码：441 / 445
页数：5
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