A systematic review of microsurgical reconstruction of the jaws using vascularized fibula flap technique in patients with bisphosphonate-related osteonecrosis

被引：19
|
作者：
Sacco, Roberto [1 ]
Sacco, Gianluca [1 ]
Acocella, Alessandro [2 ]
Sale, Silvana [1 ]
Sacco, Nicola
Baldoni, Edoardo [1 ]
机构：
[1] Univ Sassari, Fac Med, Dept Odontostomathol, I-07100 Sassari, Italy
[2] Univ Florence, Dept Oral & Maxillofacial Surg, Fac Med, Florence, Italy
来源：
JOURNAL OF APPLIED ORAL SCIENCE | 2011年 / 19卷 / 04期
关键词：
Jaw diseases; Osteonecrosis; Bisphosphonates; BONE TURNOVER; MICRODAMAGE ACCUMULATION; BIOMECHANICAL PROPERTIES; CLINICAL-EFFICACY; RISK-FACTORS; SERUM CTX; MECHANISMS; NECROSIS; RISEDRONATE; PREVENTION;
D O I：
10.1590/S1678-77572011000400001
中图分类号：
R78 [口腔科学];
学科分类号：
1003 ;
摘要：
Objective: The aim of this systematic review was to assess the role of microsurgical reconstruction of the jaws in patients with bisphosphonate-related osteonecrosis, and biological complications after an observation period of at least 12 months. Material and methods: An electronic MEDLINE search supplemented by manual searching was conducted to identify studies reporting data of at least 12 months observation on the microsurgical reconstruction of the jaws in patients with bisphosphonate-related osteonecrosis. Results: Four studies resulted eligible for the analysis yielded. Three out of five studies were free of complications, with a success rate of 100% as no recurrence of osteonecrosis was registered. Conclusions: Microsurgical reconstruction of the jaws represents a valid treatment modality in patients with bisphosphonate-related osteonecrosis at 3rd stage of the disease.
引用
收藏
页码：293 / 300
页数：8
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