A circuitous way to target p53

被引：6
|
作者：
Seton-Rogers, Sarah
机构：
来源：
NATURE REVIEWS CANCER | 2015年 / 15卷 / 06期
关键词：
D O I：
10.1038/nrc3962
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Liuet al. show that the mushroom-derived toxin α-amanitin, conjugated to antibodies against a tumour-specific biomarker, might be effective therapeutically (with minimal toxicity) for tumours that have hemizygous deletions of TP53 that also encompass POLR2A.
引用
收藏
页码：318 / 318
页数：1
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