Epiglottic Squamous Cell Carcinoma Showing Unexpected 18F-FDOPA Uptake on PET/CT Investigation

被引：4

作者：

Dietemann, Sebastien ^{[1
]}

Debry, Christian ^{[2
]}

Onea, Aline ^{[3
]}

Namer, Izzie Jacques ^{[1
,4
,5
]}

Imperiale, Alessio ^{[1
,4
,5
]}

机构：

[1] Univ Hosp Strasbourg, Dept Biophys & Nucl Med, Strasbourg, France

[2] Univ Hosp Strasbourg, Dept Otolaryngol & Maxillofacial Surg, Strasbourg, France

[3] Univ Hosp Strasbourg, Dept Pathol, Strasbourg, France

[4] Univ Strasbourg, CNRS, UMR 7357, ICube, Strasbourg, France

[5] FMTS, Fac Med, Strasbourg, France

来源：

CLINICAL NUCLEAR MEDICINE | 2015年 / 40卷 / 07期

关键词：

IN-VITRO; 3-O-METHYL-6-F-18-FLUORO-L-DOPA; TRANSPORT;

D O I：

10.1097/RLU.0000000000000818

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

We report the unexpected findings of F-18-fluorodihydroxyphenylalanine (F-18-FDOPA) PET/CT performed in a patient with a history of ileal carcinoid. A focally increased F-18-FDOPA uptake was detected in the left side of the epiglottis corresponding to a laryngeal squamous cell carcinoma. Interestingly, uptake of 3-O-methyl-6-F-18-fluoro-l-dihydroxyphenylalanine, a metabolite of F-18-FDOPA, has been previously reported in both squamous cell carcinoma cell lines and the corresponding mouse tumor xenograft models. Although F-18-FDOPA is mainly used in patients with neuroendocrine tumors, F-18-FDOPA is not a neuroendocrine tumor-specific radiotracer.

引用

页码：e370 / e371

页数：2

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