Neurobiological bases of predisposition to the development of opiate addiction

被引：1
|
作者：
Peregud, D. I. [1 ]
Panchenko, L. F. [1 ]
Gulyaeva, N. V. [2 ]
机构：
[1] Fed Agcy Publ Hlth & Social Dev, Natl Sci Ctr Narcol, Moscow, Russia
[2] Russian Acad Sci, Inst Higher Nervous Act & Neurophysiol, Moscow, Russia
来源：
NEUROCHEMICAL JOURNAL | 2008年 / 2卷 / 03期
基金：
俄罗斯基础研究基金会;
关键词：
neurobiology; opiate addiction; predisposition; biological markers; nitric oxide;
D O I：
10.1134/S1819712408030033
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
The range of individual differences in sensitivity to the pharmacological effects of psychoactive substances, especially opiates, is large. Understanding of the processes that control individual differences in the development of opiate addiction is very important for the identification of risk factors and development of effective prophylactics and therapeutic programs. We review the neurobiological bases of the predisposition to the development of opiate addiction. We also focus on the perspectives of studies of the role of the brain nitrergic system in the individual sensitivity to development of opiate addiction.
引用
收藏
页码：153 / 156
页数：4
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