Hematopoietic stem cells in transit - Where's the niche?

被引:1
|
作者
Magnusson, Mattias [1 ]
Mikkola, Hanna K. A. [1 ,2 ,3 ,4 ]
机构
[1] Univ Calif Los Angeles, Dept Mol Cellular & Dev Biol, Los Angeles, CA 90095 USA
[2] Univ Calif Los Angeles, Eli & Edythe Broad Ctr Regenerat Med & Stem Cell, Los Angeles, CA 90095 USA
[3] Univ Calif Los Angeles, Jonsson Comprehens Canc Ctr, Los Angeles, CA 90095 USA
[4] Univ Calif Los Angeles, Inst Mol Biol, Los Angeles, CA 90095 USA
关键词
D O I
10.1016/j.stem.2008.03.017
中图分类号
Q813 [细胞工程];
学科分类号
摘要
In this issue of Cell Stem Cell, Min et al. (2008) identify Egr1 as a novel hematopoietic stem cell (HSC) transcription factor that regulates proliferation and mobilization of these cells. An improved understanding of Egr1 targets may lead to better strategies to expand populations of HSCs ex vivo for therapeutic applications.
引用
收藏
页码:302 / 304
页数:3
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