Etiology and pathogenesis of multiple sclerosis

被引:39
|
作者
Sorensen, TL
Ransohoff, RM
机构
[1] Cleveland Clin Fdn, Lerner Res Inst, Dept Neurosci NC30, Cleveland, OH 44195 USA
[2] Cleveland Clin Fdn, Mellen Ctr Multiple Sclerosis Treatment & Res, Cleveland, OH 44195 USA
[3] Univ Copenhagen, Glostrup Hosp, Dept Neurol, DK-2600 Glostrup, Denmark
关键词
multiple sclerosis; pathogenesis;
D O I
10.1055/s-2008-1040879
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The cause of multiple sclerosis (MS) remains unknown despite decades of intense research, The major research disciplines that have been brought to bear on this question include genetics, epidemiology, neuropathology, immunology, and virology, Recent advances in the understanding of the inflammatory characteristics of the MS lesion may herald the development of specific and effective treatments. The goal of this research is to improve our management of a disease that remains the major cause of neurologic disability among young adults in North America and Europe.
引用
收藏
页码:287 / 294
页数:8
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