The enantioselective diethylzinc addition to imines catalyzed by chiral Cu(II)-oxazoline complexes

被引：25

作者：

Li, X ^{[1
]}

Cun, LF ^{[1
]}

Gong, LZ ^{[1
]}

Mi, AQ ^{[1
]}

Jiang, YZ ^{[1
]}

机构：

[1] Chinese Acad Sci, Chengdu Inst Organ Chem, Key Lab Asymmetr Synth & Chirotechnol Sichuan Pr, Chengdu 610041, Peoples R China

来源：

TETRAHEDRON-ASYMMETRY | 2003年 / 14卷 / 24期

关键词：

D O I：

10.1016/j.tetasy.2003.09.036

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A series of copper complexes of chiral bisoxazolines has been applied in the catalytic diethylzinc addition to N-sulfonyl imines. It has been found that the tridentate ligands 3-5 provided higher enantio selectivity than bidentate ones. Addition of 4 A molecular sieves to the reaction system benefits the enantioselectivity. The optimal procedure for diethylzinc addition to different imines resulted in moderate yields and enantioselectivities of up to 82% ee. (C) 2003 Elsevier Ltd. All rights reserved.

引用

页码：3819 / 3821

页数：3

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