Expedient Synthesis of cis- and trans-3-Aminocyclobutanecarboxylic Acids

被引：6
|
作者：
Radchenko, Dmytro S.
Tkachenko, Anton
Grygorenko, Oleksandr O. [1 ]
Komarov, Igor V.
机构：
[1] Kyiv Natl Taras Shevchenko Univ, Dept Chem, UA-01033 Kiev, Ukraine
来源：
SYNTHETIC COMMUNICATIONS | 2011年 / 41卷 / 11期
关键词：
Amino acids; conformational restriction; cyclobutanes; drug design; GABA analogs; AMINO-ACIDS; STEREOSELECTIVE-SYNTHESIS; GABA;
D O I：
10.1080/00397911.2010.491595
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
[image omitted] An expedient approach to cis- and trans-3-aminocyclobutanecarboxylic acids was developed starting from 1,1-cyclobutanedicarboxylic acid. Stereochemistry of the title compounds was established by nuclear Overhauser effect spectroscopy experiments.
引用
收藏
页码：1644 / 1649
页数：6
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