Phospholipase D (PLD) is one of the intracellular signal transduction enzymes and plays an important role in a variety of cellular functions. We investigated the expression and cellular localization of the PLD isozyme PLD1 in the rodent retina. Western blot analysis showed the presence of PLD1 at the protein level in the rat, mouse and guinea pig retinas. PLD1 immunoreactivity was localized in all Muller cells. Thus, PLD1 protein appears to be important in the functions of these cells in the rodent retina. (C) 2001 Published by Elsevier Science B.V.
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Hamadan Univ Med Sci, Neurophysiol Res Ctr, Hamadan, IranHamadan Univ Med Sci, Neurophysiol Res Ctr, Hamadan, Iran
Eftekharian, Mohammad Mahdi
Azimi, Tahereh
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Shahid Beheshti Univ Med Sci, Dept Med Genet, Fac Med, 8th Floor,SBUMS Bldg, Tehran 1983963113, IranHamadan Univ Med Sci, Neurophysiol Res Ctr, Hamadan, Iran
Azimi, Tahereh
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Ghafouri-Fard, Soudeh
Sayad, Arezou
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Shahid Beheshti Univ Med Sci, Dept Med Genet, Fac Med, 8th Floor,SBUMS Bldg, Tehran 1983963113, IranHamadan Univ Med Sci, Neurophysiol Res Ctr, Hamadan, Iran
Sayad, Arezou
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Omrani, Mir Davood
Sarrafzadeh, Shaghayegh
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Shahid Beheshti Univ Med Sci, Dept Med Genet, Fac Med, 8th Floor,SBUMS Bldg, Tehran 1983963113, IranHamadan Univ Med Sci, Neurophysiol Res Ctr, Hamadan, Iran
Sarrafzadeh, Shaghayegh
Abbasalipourkabir, Roghayeh
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Hamadan Univ Med Sci, Dept Clin Biochem, Hamadan, IranHamadan Univ Med Sci, Neurophysiol Res Ctr, Hamadan, Iran
Abbasalipourkabir, Roghayeh
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Mazdeh, Mehrdokht
Taheri, Mohammad
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Shahid Beheshti Univ Med Sci, Dept Med Genet, Fac Med, 8th Floor,SBUMS Bldg, Tehran 1983963113, Iran
Shahid Beheshti Univ Med Sci, Urogenital Stem Cell Res Ctr, Tehran, IranHamadan Univ Med Sci, Neurophysiol Res Ctr, Hamadan, Iran