Cabozantinib (C) versus placebo (P) in patients (pts) with advanced hepatocellular carcinoma (HCC) who have received prior sorafenib: results from the randomized phase 3 CELESTIAL trial

被引:0
|
作者
Waidmann, O. [1 ]
Abou-Alfa, G. K. [2 ]
Meyer, T. [3 ]
Cheng, A-L [4 ]
El-Khoueiry, A. B. [5 ]
Rimassa, L. [6 ]
Ryoo, B-Y [7 ]
Cicin, I [8 ]
Merle, P. [9 ]
Chen, Y. H. [10 ]
Park, J-W [11 ]
Blanc, J-F [12 ]
Bolondi, L. [13 ]
Klumpen, H-J [14 ]
Chan, S. L. [15 ]
Dadduzio, V [16 ]
Hessel, C. [17 ]
Borgman-Hagey, A. E. [17 ]
Schwab, G. [17 ]
Kelley, R. K. [18 ]
机构
[1] Univ Liver & Canc Ctr Frankfurt, Frankfurt, Germany
[2] Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USA
[3] Royal Free Hosp, London, England
[4] Natl Taiwan Univ Hosp, Taipei, Taiwan
[5] USC Norris Comprehens Canc Ctr, Los Angeles, CA USA
[6] Humanitas Canc Ctr, Humanitas Clin & Res Ctr, Rozzano, Italy
[7] Univ Ulsan, Coll Med, Asan Med Ctr, Seoul, South Korea
[8] Trakya Univ, Sch Med, Edirne, Turkey
[9] Groupement Hosp Lyon Nord, Lyon, France
[10] Liou Ying ChiMei Hosp, Dept Med Oncol, Tainan, Taiwan
[11] Natl Canc Ctr, Goyang, South Korea
[12] CHU, Hop Haut Leveque, Bordeaux, France
[13] Univ Bologna, Dept Med & Surg Sci, Bologna, Italy
[14] Univ Amsterdam, Dept Med Oncol, Acad Med Ctr, Amsterdam, Netherlands
[15] Chinese Univ Hong Kong, State Key Lab Oncol South China, Hong Kong, Hong Kong, Peoples R China
[16] UOC, Ist Oncol Veneto, IRCCS, Padua, Italy
[17] Exelixis Inc, San Francisco, CA USA
[18] UCSF Helen Diller Family Comprehens Canc Ctr, San Francisco, CA USA
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
V763
引用
收藏
页码:254 / 254
页数:1
相关论文
共 50 条
  • [41] Phase II trial of sorafenib (S) and capecitabine (C) for hepatocellular carcinoma (HCC) in cirrhotic patients (pts).
    Rojas-Hernandez, Cristhiam Mauricio
    Patt, Yehuda Z.
    Fekrazad, M. Houman
    Steinberg, Kim A.
    Roach, Mary
    Lee, Fa-Chyi
    JOURNAL OF CLINICAL ONCOLOGY, 2013, 31 (15)
  • [42] Tivantinib (ARQ 197) versus placebo in patients (Pts) with hepatocellular carcinoma (HCC) who failed one systemic therapy: Results of a randomized controlled phase II trial (RCT)
    Rimassa, Lorenza
    Porta, Camillo
    Borbath, Ivan
    Daniele, Bruno
    Salvagni, Stefania
    Van Laethem, Jean Luc
    Van Vlieberghe, Hans
    Trojan, Jorg
    Kolligs, Frank T.
    Weiss, Alan
    Barahona, Nancy
    Gasbarrini, Antonio
    Lencioni, Monica
    Pande, Amitkumar U.
    Lamar, Maria
    Chen, Yinpu
    Schwartz, Brian E.
    Abbadessa, Giovanni
    Santoro, Armando
    JOURNAL OF CLINICAL ONCOLOGY, 2012, 30 (15)
  • [43] Second-line cabozantinib after sorafenib treatment for advanced hepatocellular carcinoma: a subgroup analysis of the phase 3 CELESTIAL trial
    Kelley, Robin Kate
    Ryoo, Baek-Yeol
    Merle, Philippe
    Park, Joong-Won
    Bolondi, Luigi
    Chan, Stephen L.
    Lim, Ho Yeong
    Baron, Ari D.
    Parnis, Francis
    Knox, Jennifer
    Cattan, Stephane
    Yau, Thomas
    Lougheed, Julie C.
    Milwee, Steven
    El-Khoueiry, Anthony B.
    Cheng, Ann-Lii
    Meyer, Tim
    Abou-Alfa, Ghassan K.
    ESMO OPEN, 2020, 5 (04) : 1 - 9
  • [44] Phase III (COSMIC-312) study of cabozantinib (C) in combination with atezolizumab (A) vs sorafenib (S) in patients (pts) with advanced hepatocellular carcinoma (aHCC) who have not received previous systemic anticancer therapy
    Yau, T.
    Rimassa, L.
    Cheng, A-L.
    Park, J-W.
    Braiteh, F.
    Chaudhry, A.
    Benzaghou, F.
    Thuluvath, P.
    Hazra, S.
    Milwee, S.
    Tan, B.
    Sinha, R.
    Kayali, Z. K.
    Zhu, A. X.
    Kelley, R. K.
    ANNALS OF ONCOLOGY, 2019, 30
  • [45] Phase III (COSMIC-312) study of cabozantinib (C) in combination with atezolizumab (A) vs sorafenib (S) in patients (pts) with advanced hepatocellular carcinoma (aHCC) who have not received previous systemic anticancer therapy
    Rimassa, L.
    Cheng, A-L.
    Braiteh, F.
    Chaudhry, A.
    Benzaghou, F.
    Thuluvath, P.
    Hazra, S.
    Borgman-Hagey, A. E.
    Tan, B.
    Kayali, Z. K.
    Zhu, A. X.
    Kelley, R. K.
    ANNALS OF ONCOLOGY, 2019, 30 : 320 - 320
  • [46] Efficacy and safety of nintedanib versus sorafenib in Asian patients with advanced hepatocellular carcinoma (HCC): A randomized phase II trial.
    Cheng, Ann-Lii
    Yen, Chia-Jui
    Kim, Tae-You
    Feng, Yin-Hsun
    Chao, Yee
    Lin, Deng-Yn
    Loembe, Arsene-Bienvenu
    Hocke, Julia
    Choi, Caren
    Ryoo, Baek-Yeol
    JOURNAL OF CLINICAL ONCOLOGY, 2015, 33 (03)
  • [47] Cabozantinib versus everolimus in patients with advanced renal cell carcinoma: Results of the randomized phase 3 METEOR trial
    Choueiri, T.
    Escudier, B.
    Powles, T.
    Mainwaring, P.
    Rini, B.
    Donskov, F.
    Hammers, H.
    Hutson, T.
    Roth, B.
    Peltola, K.
    Lee, J. L.
    Heng, D.
    Schmidinger, M.
    Borgman-Hagey, A.
    Hessel, C.
    Scheffold, C.
    Schwab, G.
    Tannir, N.
    Motzer, R.
    EUROPEAN JOURNAL OF CANCER, 2015, 51 : S708 - S709
  • [48] Association of adverse events (AEs) with efficacy outcomes for cabozantinib (C) in patients (pts) with advanced hepatocellular carcinoma (aHCC) in the phase III CELESTIAL trial.
    Abou-Alfa, Ghassan K.
    Meyer, Tim
    Cheng, Ann-Lii
    Cicin, Irfan
    Bolondi, Luigi
    Klumpen, Heinz Josef
    Chan, Stephen Lam
    Dadduzio, Vincenzo
    Milwee, Steven
    Dubey, Sarita
    Kelley, Robin Kate
    El-Khoueiry, Anthony B.
    JOURNAL OF CLINICAL ONCOLOGY, 2019, 37 (15)
  • [49] Final analysis: Randomized, blinded, placebo-controlled phase II trial of sorafenib with and without mapatumumab in patients with advanced hepatocellular carcinoma (HCC).
    Ciuleanu, Tudor-Eliade
    Bazin, Igor
    Lungulescu, Dan
    Miron, Lucian
    Bondarenko, Igor
    Deptala, Andrzej
    Rodriguez-Torres, Maribel
    Giantonio, Bruce J.
    Sun, Weijing
    Fox, Norma Lynn
    Aktan, Gursel
    Wissel, Paul Stephen
    Egger, Jacki
    Ding, Meichun
    Kalyani, Rubana
    Gribbin, Matthew Joseph
    JOURNAL OF CLINICAL ONCOLOGY, 2014, 32 (15)
  • [50] Phase 3 (COSMIC-312) study of cabozantinib in combination with atezolizumab vs sorafenib in patients with advanced hepatocellular carcinoma (aHCC) who have not received previous systemic anticancer therapy
    Rimassa, L.
    Cheng, A.
    Braiteh, F.
    Benzaghou, F.
    Hazra, S.
    Borgman, A.
    Sinha, R.
    Kayali, Z.
    Zhu, A.
    Kelley, R.
    ANNALS OF ONCOLOGY, 2019, 30