Synthesis, Characterization, and Phytotoxic and Antifungal Activities of Biphenyl Derivatives

Three series of biphenyl derivatives are synthesized, characterized and evaluated for Lemna minor phytotoxicity and antifungal activity. The synthetic biphenyl analogues 2c and 6c demonstrate significant activity, while compounds 4b and 6b demonstrate high activity. The compounds 2c and 6c can be considered as biaryl-based potential phytotoxic agents. According to in vitro antifungal bioassay the compounds 2b, 2e, and 6b demonstrate moderate activity.