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- [35] Fatty acid synthase (FAS)-catalyzed endogenous fatty acid metabolism regulates Her-2/neu (erbB-2) oncogene expression via malonyl-coenzyme-a-dependent expression of the Ets protein polyomavirus enhancer activator 3 (PEA3), a transcriptional repressor of Her-2/neu promoter activity in cancer cells. BREAST CANCER RESEARCH AND TREATMENT, 2005, 94 : S183 - S183