Application of MerCO as a chiral catalyst in asymmetric synthesis: asymmetric borane reduction of ketones

被引：27
|
作者：
Yang, TK [1 ]
Lee, DS [1 ]
机构：
[1] Natl Chung Hsing Univ, Dept Chem, Taichung 400, Taiwan
来源：
TETRAHEDRON-ASYMMETRY | 1999年 / 10卷 / 03期
关键词：
D O I：
10.1016/S0957-4166(98)00504-7
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
The borane reduction of aryl methyl ketones catalyzed by MerCO [( 1R,2S,3R)-3-mercaptocamphan-2-ol] produced I-aryl ethyl alcohols in 92% e.e. at 50 degrees C in toluene. Significant temperature and solvent effects were observed in this reaction. (C) 1999 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：405 / 409
页数：5
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