Regulation of facioscapulohumeral muscular dystrophy candidate protein DUX4

被引:0
|
作者
Eidahl, J. [1 ]
Zhang, L. [2 ]
Hoover, M. [2 ]
Branson, O. [2 ]
Freitas, M. [2 ]
Harper, S. [1 ]
机构
[1] Nationwide Childrens Hosp, Columbus, OH USA
[2] Ohio State Univ, Columbus, OH 43210 USA
关键词
D O I
10.1016/j.nmd.2018.06.410
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
P.362
引用
收藏
页码:S139 / S139
页数:1
相关论文
共 50 条
  • [21] CRISPR mediated targeting of DUX4 distal regulatory element represses DUX4 target genes dysregulated in Facioscapulohumeral muscular dystrophy
    Sunny Das
    Brian P. Chadwick
    Scientific Reports, 11
  • [22] Inhibition of DUX4 expression with antisense LNA gapmers as a therapy for facioscapulohumeral muscular dystrophy
    Lim, Kenji Rowel Q.
    Maruyama, Rika
    Echigoya, Yusuke
    Nguyen, Quynh
    Zhang, Aiping
    Khawaja, Hunain
    Sen Chandra, Sreetama
    Jones, Takako
    Jones, Peter
    Chen, Yi-Wen
    Yokota, Toshifumi
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020, 117 (28) : 16509 - 16515
  • [23] CRISPR mediated targeting of DUX4 distal regulatory element represses DUX4 target genes dysregulated in Facioscapulohumeral muscular dystrophy
    Das, Sunny
    Chadwick, Brian P.
    SCIENTIFIC REPORTS, 2021, 11 (01)
  • [24] Morpholino-mediated Knockdown of DUX4 Toward Facioscapulohumeral Muscular Dystrophy Therapeutics
    Chen, Jennifer C. J.
    King, Oliver D.
    Zhang, Yuanfan
    Clayton, Nicholas P.
    Spencer, Carrie
    Wentworth, Bruce M.
    Emerson, Charles P., Jr.
    Wagner, Kathryn R.
    MOLECULAR THERAPY, 2016, 24 (08) : 1405 - 1411
  • [25] Loss of epigenetic silencing of the DUX4 transcription factor gene in facioscapulohumeral muscular dystrophy
    Hewitt, Jane E.
    HUMAN MOLECULAR GENETICS, 2015, 24 : R17 - R23
  • [26] p38α Regulates Expression of DUX4 in a Model of Facioscapulohumeral Muscular Dystrophy
    Rojas, L. Alejandro
    Valentine, Erin
    Accorsi, Anthony
    Maglio, Joseph
    Shen, Ning
    Robertson, Alan
    Kazmirski, Steven
    Rahl, Peter
    Tawil, Rabi
    Cadavid, Diego
    Thompson, Lorin A.
    Ronco, Lucienne
    Chang, Aaron N.
    Cacace, Angela M.
    Wallace, Owen
    JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2020, 374 (03): : 489 - 498
  • [27] Estrogens enhance myoblast differentiation in facioscapulohumeral muscular dystrophy by antagonizing DUX4 activity
    Teveroni, Emanuela
    Pellegrino, Marsha
    Sacconi, Sabrina
    Calandra, Patrizia
    Cascino, Isabella
    Farioli-Vecchioli, Stefano
    Puma, Angela
    Garibaldi, Matteo
    Morosetti, Roberta
    Tasca, Giorgio
    Ricci, Enzo
    Trevisan, Carlo Pietro
    Galluzzi, Giuliana
    Pontecorvi, Alfredo
    Crescenzi, Marco
    Deidda, Giancarlo
    Moretti, Fabiola
    JOURNAL OF CLINICAL INVESTIGATION, 2017, 127 (04): : 1531 - 1545
  • [28] Protein kinase A activation inhibits DUX4 gene expression in myotubes from patients with facioscapulohumeral muscular dystrophy
    Cruz, Joseph M.
    Hupper, Nicole
    Wilson, Liz S.
    Concannon, John B.
    Wang, Yuan
    Oberhauser, Berndt
    Patora-Komisarska, Krystyna
    Zhang, Yunyu
    Glass, David J.
    Trendelenburg, Anne-Ulrike
    Clarke, Brian A.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 293 (30) : 11837 - 11849
  • [29] Antisense strategies targeting DUX4 and DUX4c as therapeutic approaches for facioscapulohumeral muscular dystrophy (FSHD)
    Vanderplanck, C.
    Tassin, A.
    Ansseau, E.
    Lancelot, C.
    Derenne, A.
    Conotte, S.
    Dudome, V.
    Leroy, B.
    Wilton, S.
    Laoudj-Chenivesse, D.
    Wattiez, R.
    Legrand, A.
    Belayew, A.
    Coppee, F.
    NEUROMUSCULAR DISORDERS, 2015, 25 : S311 - S312
  • [30] RNA-based CRISPR off silencing to target DUX4 in facioscapulohumeral muscular dystrophy
    He, J.
    Sasaki-Honda, M.
    Tanaka, H.
    Akita, H.
    Sakurai, H.
    NEUROMUSCULAR DISORDERS, 2023, 33 : S215 - S215