Solution structure of human dihydrofolate reductase in its complex with trimethoprim and NADPH

被引：19
|
作者：
Kovalevskaya, NV
Smurnyy, YD
Polshakov, VI
Birdsall, B
Bradbury, AF
Frenkiel, T
Feeney, J
机构：
[1] Natl Inst Med Res, Div Mol Struct, London NW7 1AA, England
[2] Ctr Drug Chem, Moscow 119815, Russia
[3] Moscow MV Lomonosov State Univ, Ctr Magnet Tomog & Spect, Moscow 119992, Russia
[4] Natl Inst Med Res, MRC, Biomed NMR Ctr, London NW7 1AA, England
来源：
JOURNAL OF BIOMOLECULAR NMR | 2005年 / 33卷 / 01期
基金：
英国惠康基金; 英国医学研究理事会;
关键词：
co-operative ligand binding; dihydrofolate reductase; protein structure; protein-ligand interactions; trimethoprim;
D O I：
10.1007/s10858-005-1475-z
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
[No abstract available]
引用
收藏
页码：69 / 72
页数：4
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