Environmental contaminants and child's growth

被引:13
|
作者
Kadawathagedara, M. [1 ]
de lauzon-Guillain, B. [1 ]
Botton, J. [1 ,2 ]
机构
[1] Paris Descartes Univ, Team Early Origin Childs Hlth & Dev ORCHAD, Ctr Res Epidemiol & Stat, Sorbonne Paris Cite,INSERM,UMR1153, Paris, France
[2] Univ Paris Saclay, Univ Paris Sud, Fac Pharm, Chatenay Malabry, France
关键词
chemicals; children; epidemiology; growth; review; BODY-MASS INDEX; PERSISTENT ORGANIC POLLUTANTS; ENDOCRINE-DISRUPTING CHEMICALS; POLYBROMINATED DIPHENYL ETHERS; POLYCHLORINATED-BIPHENYLS PCBS; DIETARY ACRYLAMIDE INTAKE; BISPHENOL-A EXPOSURE; EARLY-LIFE EXPOSURE; PRENATAL EXPOSURE; BIRTH-WEIGHT;
D O I
10.1017/S2040174418000995
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Experimental data have suggested that some contaminants in the environment may increase the risk of obesity. Infants can be exposed to chemicals either prenatally, by trans-placental passage of chemicals, or postnatally by their own diet and by other external pathways (air inhalation, dust, hand-to-mouth exposure) after birth. To provide a review of epidemiological evidence on the association between prenatal exposure to chemicals and prenatal and postnatal growth, we present the literature from systematic review articles and international meta-analyses, when available, or recent research articles when summarizing articles were not available. The most studied contaminants in this field were persistent organic pollutants (e.g. organochlorinated pesticides, polychlorinated biphenyls), non-persistent pollutants (e.g. phthalates, bisphenol A), toxic heavy metals (i.e. cadmium, lead and mercury), arsenic, mycotoxins and acrylamide. Mounting evidence suggests that child's growth may be associated with prenatal or postnatal exposures to environmental contaminants. Improving exposure assessment and studying the contaminants as mixtures should allow to gain knowledge about the environmental determinants of growth and obesity.
引用
收藏
页码:632 / 641
页数:10
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