Improved signal extraction method for single-pulse heterodyne CARS spectroscopy

被引：2
|
作者：
Nagashima, Yu [2 ]
Suzuki, Takayuki [1 ]
Terada, Sumio [3 ]
Tsuji, Shoji [2 ]
Misawa, Kazuhiko [1 ]
机构：
[1] Tokyo Univ Agr & Technol, Dept Appl Phys, 2-24-16 Naka Cho, Koganei, Tokyo 1848588, Japan
[2] Univ Tokyo, Grad Sch Med, Dept Neurol, Bunkyo Ku, Tokyo 1138655, Japan
[3] Tokyo Med & Dent Univ, Grad Sch Med & Dent Sci, Dept Syst Neurosci, Sect Neuroanat & Cellular Neurobiol, Tokyo 1138519, Japan
来源：
LASER APPLICATIONS IN LIFE SCIENCES | 2010年 / 7376卷
关键词：
coherent anti-Stokes Raman scattering; matched filter; heterodyne detection; chloroform;
D O I：
10.1117/12.871162
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
Single-pulse heterodyne CARS (coherent anti-Stokes Raman scattering) detection scheme using shaped femtosecond pulses is one of the most sophisticated approach for managing the problem of non-resonant background disturbance in CARS measurement. However, with the signal processing method conducted in the original report,(1-3) we found that background suppression and resonant peak extraction were sometimes difficult and incomplete. We discuss the reason of this unsuccessful signal processing and propose an improved method for signal extraction realizing the better quality of extracted spectra.
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页数：6
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