Prevention and treatment of adverse effects of corticosteroids in systemic lupus erythematosus

被引:11
|
作者
Ginzler, EM [1 ]
Aranow, C [1 ]
机构
[1] SUNY Hlth Sci Ctr, Div Rheumatol, Brooklyn, NY 11203 USA
来源
BAILLIERES CLINICAL RHEUMATOLOGY | 1998年 / 12卷 / 03期
关键词
corticosteroids; steroid toxicity; infection; osteoporosis; avascular necrosis; peptic ulcer disease;
D O I
10.1016/S0950-3579(98)80032-0
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Corticosteroid therapy has had a major impact on improvement in disease activity and long-term survival in patients with systemic lupus erythematosus (SLE). Unfortunately, the therapeutic advantages are accompanied by many manifestations of toxicity, some of which are short term and potentially reversible, while others cause chronic irreversible damage. Many of these features of toxicity have similar presentations to manifestations of SLE disease activity, and must be distinguished in the individual patient. The features of corticosteroid toxicity are reviewed in this chapter, and means of prevention and/or treatment are discussed.
引用
收藏
页码:495 / 510
页数:16
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