Were the wrong cells studied?

被引：1
|
作者：
Koppe, Janna [1 ]
Ten Tusscherb, Gavin W. [2 ]
机构：
[1] Univ Amsterdam, Emma Childrens Hosp AMC, Dept Pulmonol, NL-3634 AT Loenersloot, Netherlands
[2] Westfriesgasthuis, Dept Paediat & Neonatol, Hoorn, Netherlands
来源：
TOXICOLOGY LETTERS | 2015年 / 232卷 / 02期
关键词：
Lymphocytes; Polymorphonuclear leucocytes; Ah-receptor; Dioxin; Dioxin-like compound; Toxic equivalent factor (TEF); EXPOSURE; EXPRESSION; DIOXINS;
D O I：
10.1016/j.toxlet.2014.10.002
中图分类号：
R99 [毒物学（毒理学）];
学科分类号：
100405 ;
摘要：
Peripheral blood lymphocytes (PBL) studying the effects of dioxins and dioxin-like compounds in vitro is not correct. Peripheral lymphocytes in general (Th1, Th2) do not have an Ah-receptor. Polymorphonuclear leucocytes (PMN's) are more logical to use. (c) 2014 Elsevier Ireland Ltd. All rights reserved.
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页码：542 / 543
页数：2
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