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Were the wrong cells studied?
被引:1
|作者:
Koppe, Janna
[1
]
Ten Tusscherb, Gavin W.
[2
]
机构:
[1] Univ Amsterdam, Emma Childrens Hosp AMC, Dept Pulmonol, NL-3634 AT Loenersloot, Netherlands
[2] Westfriesgasthuis, Dept Paediat & Neonatol, Hoorn, Netherlands
关键词:
Lymphocytes;
Polymorphonuclear leucocytes;
Ah-receptor;
Dioxin;
Dioxin-like compound;
Toxic equivalent factor (TEF);
EXPOSURE;
EXPRESSION;
DIOXINS;
D O I:
10.1016/j.toxlet.2014.10.002
中图分类号:
R99 [毒物学(毒理学)];
学科分类号:
100405 ;
摘要:
Peripheral blood lymphocytes (PBL) studying the effects of dioxins and dioxin-like compounds in vitro is not correct. Peripheral lymphocytes in general (Th1, Th2) do not have an Ah-receptor. Polymorphonuclear leucocytes (PMN's) are more logical to use. (c) 2014 Elsevier Ireland Ltd. All rights reserved.
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页码:542 / 543
页数:2
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