Decoding the Noncoding Cancer Genome

被引：0
|
作者：
van Galen, Peter [1 ,2 ,3 ]
机构：
[1] Brigham & Womens Hosp, Div Hematol, Boston, MA 02115 USA
[2] Harvard Med Sch, Dept Med, Boston, MA 02115 USA
[3] Broad Inst MIT & Harvard, Cambridge, MA 02142 USA
来源：
CANCER DISCOVERY | 2020年 / 10卷 / 05期
关键词：
TERT PROMOTER MUTATIONS; RECURRENT;
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
In this issue of Cancer Discovery, Li and colleagues provide a blueprint for the identification and functional validation of cancer-associated mutations in noncoding regions of the genome. Integration of whole-genome sequencing and high-throughput epigenome editing screens is starting to reveal the extent to which noncoding genetic lesions contribute to cancer.
引用
收藏
页码：646 / 647
页数：2
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