Heavy prenatal alcohol exposure and risk of stillbirth and preterm delivery

被引：19
|
作者：
Cornman-Homonoff, Joshua [1 ,2 ]
Kuehn, Devon [1 ,3 ]
Aros, Sofia [4 ]
Carter, Tonia C. [1 ]
Conley, Mary R. [1 ]
Troendle, James [5 ]
Cassorla, Fernando [6 ]
Mills, James L. [1 ]
机构：
[1] Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Div Epidemiol Stat & Prevent Res, NIH, Dept Hlth & Human Serv, Bethesda, MD USA
[2] Univ Penn, Sch Med, Philadelphia, PA 19104 USA
[3] Uniformed Serv Univ Hlth Sci, Dept Pediat, Bethesda, MD 20814 USA
[4] Univ Chile, Fac Med, Dept Pediat, San Borja Arriaran Clin Hosp, Santiago 7, Chile
[5] NHLBI, Div Cardiovasc Sci, NIH, Dept Hlth & Human Serv, Bethesda, MD 20892 USA
[6] Univ Chile, Fac Med, Inst Maternal & Child Res IDIMI, Santiago 7, Chile
来源：
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE | 2012年 / 25卷 / 06期
关键词：
alcohol; pregnancy; stillbirth; preterm delivery; binge drinking; PREGNANCY; DEATH; CONSUMPTION; MORTALITY; DRINKING; BIRTH; CHILE;
D O I：
10.3109/14767058.2011.587559
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
We prospectively identified 96 women consuming at least 4 drinks/day during pregnancy by screening 9628 pregnant women. In these women with heavy prenatal alcohol use, there were three stillbirths and one preterm delivery; 98 matched nondrinking women had no stillbirths and two preterm births. Preterm rates did not differ significantly. The stillbirth rate was higher in the exposed group (p = 0.06). Additional investigation showed the stillbirth rate in the exposed population (3.1%) was significantly higher (p = 0.019) than the reported Chilean population rate (0.45%). Our data suggest that heavy alcohol consumption may increase the risk for stillbirth but not preterm delivery.
引用
收藏
页码：860 / 863
页数：4
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