Since its successful launch in June 2008, the Fermi Gamma-ray Space Telescope has made important breakthroughs in the understanding of the Gamma-Ray Burst (GRB) phenomenon. The combination of the GBM and the LAT instruments on-board the Fermi observatory has provided a wealth of information from its observations of GRBs over seven decades in energy. We present brief descriptions of the Fermi instruments and their capabilities for GRB science, and report highlights from Fermi observations of high-energy prompt and extended GRB emission. The main physical implications of these results are discussed, along with open questions regarding GRB modeling. We emphasize future synergies with ground-based Cerenkov telescopes at the time of the SVOM mission. (C) 2011 Academie des sciences. Published by Elsevier Masson SAS. All rights reserved.