Interference-contrast optical activity: a new technique for probing the chirality of anisotropic samples and more

被引：1
|
作者：
Cameron, R. P. [1 ,2 ]
Vogl, U. [3 ]
Trautmann, N. [3 ]
机构：
[1] SUPA, Glasgow G4 0NG, Lanark, Scotland
[2] Univ Strathclyde, Dept Phys, Glasgow G4 0NG, Lanark, Scotland
[3] Carl Zeiss, Corp Res & Technol, Carl Zeiss Str 22, D-73447 Oberkochen, Germany
来源：
ROYAL SOCIETY OPEN SCIENCE | 2020年 / 7卷 / 05期
关键词：
chirality; optical activity; polarization; polarimetry; microscopy; DIC; DOWN POLARIMETRY CRDP; CIRCULAR-DICHROISM; APPARATUS HAUP; BIREFRINGENCE; CRYSTALS; ROTATION;
D O I：
10.1098/rsos.192201
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
We introduce interference-contrast optical activity (ICOA) as a new technique for probing the chirality of anisotropic samples and more. ICOA could underpin a new class of 'chiral microscopes', with potential applications spanning the range of chirality and beyond. Two possible versions of ICOA are described explicitly; one designed to probe the optical rotation of a transparent sample regardless of the sample's linear birefringence (ICOA-OR) and another designed to probe gradients in the optical rotation of a transparent sample (ICOA-GOR). Simulated results for alpha-quartz lead us to suggest that ICOA-GOR might be applied to help monitor the growth of chiral crystals in the pharmaceutical industry. Possible directions for future research are highlighted.
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页数：17
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