Rapid synthesis of 2,5-disubtituted 1,3,4-thiadiazoles under microwave irradiation

被引：49
|
作者：
Lebrini, M
Bentiss, F
Lagrenée, M
机构：
[1] ENSCL, CNRS, UMR 8012, Lab Cristallochim & Physicochim Solide, F-59652 Villeneuve Dascq, France
[2] Univ Chouaib Doukkali, Fac Sci, Lab Chim Coordinat & Analyt, El Jadida, Morocco
来源：
JOURNAL OF HETEROCYCLIC CHEMISTRY | 2005年 / 42卷 / 05期
关键词：
D O I：
10.1002/jhet.5570420538
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The one pot, three-components condensation of aromatic aldehydes, hydrazine and sulfur in ethanol under microwave irradiation provided symmetrically 3,5-disubstituted 1,3,4-thiadiazoles in high yields and good purity. This reaction must be conducted under pressure of hydrogen sulfide produced in-situ. The structure of the compounds was confirmed by H-1, C-13 NMR, MS and elemental analysis.
引用
收藏
页码：991 / 994
页数：4
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