NO supports tumor growth by suppression of lymphocytes - Experiments in vivo

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作者
Leder, GH
Oppenheim, M
Rosenstein, M
Hoffman, R
Lotze, MT
Beger, HG
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R61 [外科手术学];
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Decreased NO synthesis was associated with reduced mean tumor growth in a murine metastasis model but when lymphocytes were simultaneously stimulated with IL-2 high NO levels even were antitumoral. NO therefore may act both tumor promoting and, only as long as lymphocytes are stimulated, inhibitory.
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页码:181 / 184
页数:4
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