3-Thio-1,2,4-triazoles, novel somatostatin sst2/sst5 agonists

被引：41
|
作者：
Contour-Galcéra, MO [1 ]
Sidhu, A [1 ]
Plas, P [1 ]
Roubert, P [1 ]
机构：
[1] Inst Henri Beaufour, Ipsen Res Labs, F-91966 Les Ulis, France
来源：
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2005年 / 15卷 / 15期
关键词：
somatostatin agonist; somatostatin subtypes 2 and 5 agonist; 3-thio-triazole;
D O I：
10.1016/j.bmcl.2005.05.061
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Novel 3-thio-1,2,4-triazoles have been obtained via a solution-phase parallel synthesis strategy, affording potent non-peptidic human somatostatin receptor subtypes 2 and 5 agonists. (c) 2005 Elsevier Ltd. All rights reserved.
引用
收藏
页码：3555 / 3559
页数：5
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