Detection of NDM-1-Producing Klebsiella pneumoniae in Kenya

被引:160
|
作者
Poirel, Laurent [1 ]
Revathi, Gunturu [2 ]
Bernabeu, Sandrine [1 ]
Nordmann, Patrice [1 ]
机构
[1] Hop Bicetre, AP HP, Fac Med Paris Sud, Serv Bacteriol Virol,INSERM,U914 Emerging Resista, K Bicetre, France
[2] Aga Khan Univ Hosp, Dept Pathol, Nairobi, Kenya
关键词
BETA-LACTAMASE; CARBAPENEMASES; EMERGENCE;
D O I
10.1128/AAC.01247-10
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Seven carbapenem-resistant NDM-1-positive Klebsiella pneumoniae isolates were recovered from patients hospitalized between 2007 and 2009 in different wards at a referral and tertiary care center in Nairobi. Most of the isolates were obtained from urine. All isolates carried the bla(NDM-1) carbapenemase gene previously reported from India, Pakistan, and the United Kingdom. These isolates were clonally related and expressed many other resistance determinants, including beta-lactamases CTX-M-15, OXA-1, OXA-9, CMY-6, and aminoglycoside resistance methylase RmtC. This work corresponds to the first report of NDM-1 producers in Africa.
引用
收藏
页码:934 / 936
页数:3
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