High dose intravenous immunoglobulin treatment: Mechanisms of action

被引：44
|
作者：
Boros, P
Gondolesi, G
Bromberg, AS
机构：
[1] Mt Sinai Sch Med, Recanati Miller Transplantat Inst, New York, NY 10029 USA
[2] Mt Sinai Sch Med, Dept Gene & Cell Med, New York, NY USA
来源：
LIVER TRANSPLANTATION | 2005年 / 11卷 / 12期
关键词：
D O I：
10.1002/lt.20594
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Intravenous immunoglobulin (IVIg) treatment was introduced as replacement therapy for patients with antibody deficiencies, but evidence suggests that a wide range of immune-mediated conditions could benefit from IVIg. The immunoglobulins are precipitated from human plasma by fractionation methods. In conclusion, the differences in basic fractionation methods and the addition of various modifications for purification, stabilization, and virus inactivation result in products significantly different from each other.
引用
收藏
页码：1469 / 1480
页数：12
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