One-step functionalization of magnetic nanoparticles with 4-mercaptophenylboronic acid for a highly efficient analysis of N-glycopeptides

被引:51
|
作者
Yao, Jizong [1 ,2 ]
Wang, Jiawen [1 ,2 ]
Sun, Nianrong [1 ,2 ]
Deng, Chunhui [1 ,2 ]
机构
[1] Fudan Univ, Collaborat Innovat Ctr Genet & Dev, Dept Chem, Shanghai 200433, Peoples R China
[2] Fudan Univ, Collaborat Innovat Ctr Genet & Dev, Inst Biomed Sci, Shanghai 200433, Peoples R China
基金
中国国家自然科学基金;
关键词
DISTILLATION PRECIPITATION POLYMERIZATION; SELECTIVE ENRICHMENT; FACILE SYNTHESIS; GOLD NANOPARTICLES; GLYCOPROTEINS; MICROSPHERES; RECOGNITION; GLYCOSYLATION;
D O I
10.1039/c7nr04206j
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A very simple and amazing approach was proposed to synthesize MPBA functionalized magnetic nanoparticles via the interaction between Fe and SH, and the as-prepared nanoparticles were successfully applied for the efficient analysis of glycopeptides in complex bio-samples with sensitivity and selectivity.
引用
收藏
页码:16024 / 16029
页数:6
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