SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF 2H-[1]-BENZOPYRAN-2-ONE DERIVATIVES. COMPARISON WITH STREPTOMYCIN

被引：0

作者：

Behrami, A. ^{[2
]}

Vaso, K. ^{[1
]}

Leci, O. ^{[2
]}

Plakolli, M. ^{[2
]}

Krasniqi, I. ^{[2
]}

Vehapi, I. ^{[3
]}

机构：

[1] Univ Tirana, Fac Nat Sci, Dept Chem, Tirana, Albania

[2] Univ Prishtina, Dept Chem, Prishtina, Kosova, Serbia

[3] Univ Prishtina, Dept Biol, Prishtina, Kosova, Serbia

来源：

JOURNAL OF ENVIRONMENTAL PROTECTION AND ECOLOGY | 2011年 / 12卷 / 02期

关键词：

benzopyran-2-one; antibacterial activity; Escherichia coli; Staphylococcus aureus; streptomycin; COUMARIN;

D O I：

暂无

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Benzopyranones of 4-hydoxy-3-nitro-2H-[1]-benzopyran-2-one (2); 4-chloro-3-nitro-2 H-[1]-benzopyran-2-one (3); 4-(2-naphthylamino)-3-nitro-2 H-[1]-benzopyran-2-one (4); 4-(4-amino-2,6-dihydroxypirimidine)-3-nitro-2H-[1]-benzopyran-2-one (5); 4-[N-ethylhydrazino]-2H-[1]-benzopyran-2-one (6); 4-butylamino-2H-[1]-benzopyran-2-one (7), have been synthesised and characterised using elemental analysis, IR spectra, H-1 NMR and C-13 NMR spectra. The antibacterial activity of all synthesised compounds and standard drug (streptomycin) has been evaluated against two strains of bacterial culture: Staphylococcus aureus and Escherichia coli. The compounds show bacteriostatic and bactericidal activity.

引用

页码：652 / 660

页数：9

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