SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF 2H-[1]-BENZOPYRAN-2-ONE DERIVATIVES. COMPARISON WITH STREPTOMYCIN

被引：0
|
作者：
Behrami, A. [2 ]
Vaso, K. [1 ]
Leci, O. [2 ]
Plakolli, M. [2 ]
Krasniqi, I. [2 ]
Vehapi, I. [3 ]
机构：
[1] Univ Tirana, Fac Nat Sci, Dept Chem, Tirana, Albania
[2] Univ Prishtina, Dept Chem, Prishtina, Kosova, Serbia
[3] Univ Prishtina, Dept Biol, Prishtina, Kosova, Serbia
来源：
JOURNAL OF ENVIRONMENTAL PROTECTION AND ECOLOGY | 2011年 / 12卷 / 02期
关键词：
benzopyran-2-one; antibacterial activity; Escherichia coli; Staphylococcus aureus; streptomycin; COUMARIN;
D O I：
暂无
中图分类号：
X [环境科学、安全科学];
学科分类号：
08 ; 0830 ;
摘要：
Benzopyranones of 4-hydoxy-3-nitro-2H-[1]-benzopyran-2-one (2); 4-chloro-3-nitro-2 H-[1]-benzopyran-2-one (3); 4-(2-naphthylamino)-3-nitro-2 H-[1]-benzopyran-2-one (4); 4-(4-amino-2,6-dihydroxypirimidine)-3-nitro-2H-[1]-benzopyran-2-one (5); 4-[N-ethylhydrazino]-2H-[1]-benzopyran-2-one (6); 4-butylamino-2H-[1]-benzopyran-2-one (7), have been synthesised and characterised using elemental analysis, IR spectra, H-1 NMR and C-13 NMR spectra. The antibacterial activity of all synthesised compounds and standard drug (streptomycin) has been evaluated against two strains of bacterial culture: Staphylococcus aureus and Escherichia coli. The compounds show bacteriostatic and bactericidal activity.
引用
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页码：652 / 660
页数：9
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