Differential functions of mTORC1 and mTORC2 in the maintenance of stem-like properties of pancreatic cancer cells

被引：0
|
作者：
Matsubara, Shyuichiro [1 ]
Tsukasa, Koichiro [1 ]
Kuwahata, Taisaku [1 ]
Obara, Toru [1 ]
Matsuyama, Takami [1 ]
Takao, Sonshin [1 ,2 ]
机构：
[1] Kagoshima Univ, Sch Med, Canc & Regenerat Med, Kagoshima, Japan
[2] Tanegashima Med Ctr, Nishinoomote, Japan
来源：
CANCER SCIENCE | 2018年 / 109卷
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
J-2063
引用
收藏
页码：703 / 703
页数：1
相关论文
共 50 条
  • [41] Opposite Roles of mTORC1 and mTORC2 in Liver Ischemia and Reperfusion Injury
    Zhou, H.
    Zhu, J.
    Kupiec-Weglinski, J.
    Busuttil, R.
    Zhai, Y.
    TRANSPLANTATION, 2017, 101 (05) : 109 - 109
  • [42] Differential regulation of mTORC1 and mTORC2 is critical for 8-Br-cAMP-induced decidualization
    Mi-Ock Baek
    Hae-In Song
    Joong-Soo Han
    Mee-Sup Yoon
    Experimental & Molecular Medicine, 2018, 50 : 1 - 11
  • [43] mTORC1 and mTORC2 regulate skin morphogenesis and epidermal barrier formation
    Ding, Xiaolei
    Bloch, Wilhelm
    Iden, Sandra
    Ruegg, Markus A.
    Hall, Michael N.
    Leptin, Maria
    Partridge, Linda
    Eming, Sabine A.
    NATURE COMMUNICATIONS, 2016, 7 : 13226
  • [44] Therapeutic implications of mTORC1 and mTORC2 inhibitors in genetically heterogeneous glioblastoma
    Amin, Anubhav G.
    Wang, Arthur
    Braun, Alex
    Tobias, Michael
    Murali, Raj
    Jhanwar-Uniyal, Meena
    CANCER RESEARCH, 2017, 77
  • [45] Involvement of mTORC1 and mTORC2 in regulation of glioblastoma multiforme growth and motility
    Gulati, Nicholas
    Karsy, Michael
    Albert, Ladislau
    Murali, Raj
    Jhanwar-Uniyal, Meena
    INTERNATIONAL JOURNAL OF ONCOLOGY, 2009, 35 (04) : 731 - 740
  • [46] Dopamine neuron morphology and output are differentially controlled by mTORC1 and mTORC2
    Kosillo, Polina
    Ahmed, Kamran M.
    Aisenberg, Erin E.
    Karalis, Vasiliki
    Roberts, Bradley M.
    Cragg, Stephanie J.
    Bateup, Helen S.
    ELIFE, 2022, 11
  • [47] mTORC1 and mTORC2 regulate skin morphogenesis and epidermal barrier formation
    Xiaolei Ding
    Wilhelm Bloch
    Sandra Iden
    Markus A. Rüegg
    Michael N. Hall
    Maria Leptin
    Linda Partridge
    Sabine A. Eming
    Nature Communications, 7
  • [48] AZD2014, a dual mTORC1 and mTORC2 inhibitor is differentiated from allosteric inhibitors of mTORC1 in ER+ breast cancer
    Guichard, Sylvie M.
    Howard, Zoe
    Heathcote, Dan
    Roth, Mark
    Hughes, Gareth
    Curwen, Jon
    Yates, James
    Logie, Armelle
    Holt, Sarah
    Chresta, Christine M.
    Davies, Barry R.
    Malagu, Karine
    Hummersone, Marc
    Pass, Sarah L.
    Green, Stephen
    Pass, Martin
    CANCER RESEARCH, 2012, 72
  • [49] Rapamycin inhibits mSin1 phosphorylation independently of mTORC1 and mTORC2
    Luo, Yan
    Liu, Lei
    Wu, Yang
    Singh, Karnika
    Su, Bing
    Zhang, Nan
    Liu, Xiaowei
    Shen, Yangmei
    Huang, Shile
    ONCOTARGET, 2015, 6 (06) : 4286 - 4298
  • [50] mTORC1 and mTORC2 Regulates Placental Amino Acid Transporters.
    Rosario, Fredrick J.
    Powell, Theresa L.
    Jansson, Thomas
    REPRODUCTIVE SCIENCES, 2010, 17 (03) : 259A - 259A
12345