Precursor lymphoblastic lymphoma reoccurring as a donor-derived neoplasm - A case report and review of the literature

被引:0
|
作者
Dickson, Brendan C. [2 ,3 ]
Chung, Catherine T. -S. [2 ,3 ]
Patterson, Bruce J. [4 ]
Riddell, Robert H. [2 ,3 ]
Kamel-Reid, Suzanne [4 ]
Messner, Hans A. [1 ]
Lipton, Jeffrey H. [1 ]
机构
[1] Univ Hlth Network, Dept Hematol & Med Oncol, Ontario Canc Inst, Toronto, ON M5G 2M9, Canada
[2] Univ Toronto, Dept Pathol & Lab Med, Mt Sinai Hosp, Toronto, ON, Canada
[3] Univ Toronto, Dept Lab Med & Pathobiol, Mt Sinai Hosp, Toronto, ON, Canada
[4] Univ Hlth Network, Dept Pathol, Toronto, ON, Canada
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中图分类号
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号
1001 ;
摘要
Precursor lymphoblastic lymphoma is an uncommon neoplasm. We report the case of a man who presented with precursor T lymphoblastic lymphoma and ultimately received an allogeneic bone marrow transplant from his human leukocyte antigen-identical sister. Four years later he developed recurrent disease. By means of DNA probing for the amelogenin locus and fluorescence in situ hybridization, the neoplastic cells of the recurrent lesion were found to be of donor origin. We offer the report of a patient with an unusual lymphoblastic lymphoma who, after successful bone marrow transplantation, developed the same disease of donor cell origin; further, we offer a literature review on donor cell lymphoma.
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页码:1342 / 1345
页数:4
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