Monitoring bone loss using ELISA and surface plasmon resonance (SPR) technology

被引：11
|
作者：
Lung, FDT
Chen, HY
Lin, HT
机构：
[1] China Med Coll, Dept Nutr, Taichung 404, Taiwan
[2] China Med Coll Hosp, Dept Obstet & Gynecol, Taichung, Taiwan
来源：
PROTEIN AND PEPTIDE LETTERS | 2003年 / 10卷 / 03期
关键词：
osteoporosis; bone turnover; bone resorption; N-telopeptide; ELISA; surface plasmon resonance;
D O I：
10.2174/0929866033478997
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Osteoporosis influences the health of the females who are in menopause phase. The techniques to detect the markers of bone turnover is very important for preventing osteoporosis. ELISA was developed for detection of urinary N-telopeptide (NTx) as an osteoporosis marker. Our aim is to develop a sensitive method to detect NTx excretion using surface plasmon resonance (SPR). Samples collected were assayed and results suggest that our SPR-based method is promising for monitoring bone loss.
引用
收藏
页码：313 / 319
页数：7
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