Inhibition of SUMOylation modulates the immunosuppressive microenvironment of pancreatic cancer

被引:0
|
作者
Erdem, S. [1 ,2 ]
Narayanan, J. S. [1 ]
Mohottige Don, N. [1 ]
Worni, M. [2 ,3 ]
White, R. R. [1 ]
Chen, Y. [1 ]
机构
[1] Univ Calif San Diego UCSD, Moores Canc Ctr, San Diego, CA USA
[2] Clarunis Univ, Dept Visceral Surg, Abdominal Ctr, Basel, Switzerland
[3] Hirslanden Hosp Beau Site, Dept Visceral Surg, Bern, Switzerland
关键词
D O I
10.1093/bjs/znac178.008
中图分类号
R61 [外科手术学];
学科分类号
摘要
引用
收藏
页数:2
相关论文
共 50 条
  • [21] Myeloid-derived TNF Orchestrates Immunosuppressive Networks in the Pancreatic Cancer Tumor Microenvironment
    Bianchi, A.
    Silva, I. De Castro
    Deshpande, N.
    Mehra, S.
    Dosch, A.
    Singh, S.
    Merchant, N.
    Datta, J.
    PANCREAS, 2021, 50 (07) : 1047 - 1048
  • [22] Improving CAR T cell function by reversing the immunosuppressive tumor microenvironment of pancreatic cancer
    Mohammed, Somala
    Sukumaran, Sujita
    Bajgain, Pradip
    Anurathapan, Usanarat
    Heslop, Helen E.
    Rooney, Cliona M.
    Brenner, Malcolm K.
    Leen, Ann M.
    Vera, Juan F.
    CANCER RESEARCH, 2015, 75
  • [23] Targeting tumor immunosuppressive microenvironment for pancreatic cancer immunotherapy: Current research and future perspective
    Li, Ying
    Xiang, Shuai
    Pan, Wenjun
    Wang, Jing
    Zhan, Hanxiang
    Liu, Shanglong
    FRONTIERS IN ONCOLOGY, 2023, 13
  • [24] Fibroblast-specific IL1 receptor inhibition reprograms the inflammatory stroma to overcome the immunosuppressive tumor microenvironment in pancreatic cancer
    Acevedo, Camille
    Singh, Samara
    Dosch, Austin
    Box, Edmond W.
    Silva, Iago C.
    Bianchi, Anna
    Mehra, Siddharth
    Amirian, Haleh
    Adams, Andrew
    Nagathihalli, Nagaraj
    Datta, Jashodeep
    Merchant, Nipun B.
    CANCER RESEARCH, 2024, 84 (17)
  • [25] Pancreatic cancer cell-derived migrasomes promote cancer progression by fostering an immunosuppressive tumor microenvironment
    Zhang, Ronghua
    Peng, Junya
    Zhang, Yalu
    Zheng, Kexin
    Chen, Yang
    Liu, Lulu
    Li, Tong
    Liu, Jingkai
    Li, Ying
    Yang, Sen
    Wang, Mengyi
    Cui, Ming
    Zhang, Xiang
    Gao, Junyi
    Kleeff, Jorg
    Liao, Quan
    Liu, Qiaofei
    CANCER LETTERS, 2024, 605
  • [26] Elucidation of immunosuppressive microenvironment in colorectal cancer
    Sasada, Tetsuro
    Ohtake, Junya
    Satoyoshi, Tetsuta
    Kazama, Keisuke
    Wada, Satoshi
    Yada, Erika
    Shiozawa, Manabu
    CANCER RESEARCH, 2018, 78 (13)
  • [27] Suppression of prostate cancer and amelioration of the immunosuppressive tumor microenvironment through selective immunoproteasome inhibition
    Koerner, Julia
    Horvath, Dennis
    Oliveri, Franziska
    Li, Jun
    Basler, Michael
    ONCOIMMUNOLOGY, 2023, 12 (01):
  • [28] Thrombin inhibition and cisplatin block tumor progression in ovarian cancer by alleviating the immunosuppressive microenvironment
    Alexander, Eric T.
    Minton, Allyson R.
    Peters, Molly C.
    van Ryn, Joanne
    Gilmour, Susan K.
    ONCOTARGET, 2016, 7 (51): : 85291 - 85305
  • [29] The Pancreatic Cancer Microenvironment
    Dougan, Stephanie K.
    CANCER JOURNAL, 2017, 23 (06): : 321 - 325
  • [30] Pancreatic cancer microenvironment
    Kleeff, Joerg
    Beckhove, Philipp
    Esposito, Irene
    Herzig, Stephan
    Huber, Peter E.
    Loehr, J. Matthias
    Friess, Helmut
    INTERNATIONAL JOURNAL OF CANCER, 2007, 121 (04) : 699 - 705