Inhibition of SUMOylation modulates the immunosuppressive microenvironment of pancreatic cancer

被引:0
|
作者
Erdem, S. [1 ,2 ]
Narayanan, J. S. [1 ]
Mohottige Don, N. [1 ]
Worni, M. [2 ,3 ]
White, R. R. [1 ]
Chen, Y. [1 ]
机构
[1] Univ Calif San Diego UCSD, Moores Canc Ctr, San Diego, CA USA
[2] Clarunis Univ, Dept Visceral Surg, Abdominal Ctr, Basel, Switzerland
[3] Hirslanden Hosp Beau Site, Dept Visceral Surg, Bern, Switzerland
关键词
D O I
10.1093/bjs/znac178.008
中图分类号
R61 [外科手术学];
学科分类号
摘要
引用
收藏
页数:2
相关论文
共 50 条
  • [1] Inhibition of SUMOylation Modulates the Immunosuppressive Microenvironment of Pancreatic Cancer
    Erdem, Suna
    Narayanan, Jayanth Shankara
    Don, Neranjan Mohottige
    Worni, Mathias
    White, Rebekah R.
    Chen, Yuan
    SWISS MEDICAL WEEKLY, 2022, 152 : 30S - 30S
  • [3] OSBPL3 modulates the immunosuppressive microenvironment and predicts therapeutic outcomes in pancreatic cancer
    Sun, Qihui
    Zhu, Xiaoqi
    Zou, Qi
    Chen, Yang
    Wen, Tingting
    Jiang, Tingting
    Li, Xiaojia
    Wei, Fang
    Xie, Keping
    Liu, Jia
    BIOLOGY DIRECT, 2025, 20 (01)
  • [4] Acquired resistance to KRAS inhibition modulates the pancreatic cancer tumor microenvironment
    Gulay, Kevin Christian Montecillo
    Patel, Jay
    Ng, Isabella
    De Mendoza, Tatiana Hurtado
    Tiriac, Herve
    Lowy, Andrew
    CANCER RESEARCH, 2024, 84 (02)
  • [5] Aging modulates the tumor microenvironment of pancreatic cancer
    Henriquez, Joaquin Araos
    Manansala, Judhell
    Teles, Sara Pinto
    Jihad, Muntadher
    Lloyd, Eloise G.
    Jassim, Amir
    Gilbertson, Richard J.
    Biffi, Giulia
    CANCER RESEARCH, 2022, 82 (22)
  • [6] Inhibition of SUMOylation Induces Adaptive Antitumor Immunity against Pancreatic Cancer through Multiple Effects on the Tumor Microenvironment
    Erdem, Suna
    Lee, Hyojae James
    Narayanan, Jayanth Surya Narayanan Shankara
    Tharuka, Mohottige Don Neranjan
    de la Torre, Jorge
    Ren, Tianchen
    Kuang, Yixuan
    Abeywardana, Tharindumala
    Li, Kevin
    Berger, Allison J.
    Lowy, Andrew M.
    White, Rebekah R.
    Chen, Yuan
    MOLECULAR CANCER THERAPEUTICS, 2024, 23 (11) : 1597 - 1612
  • [7] IMMUNOSUPPRESSIVE MICROENVIRONMENT IN PANCREATIC ADENOCARCINOMA
    Svetlana, Karakhanova
    Jens, Werner
    Alexandr, Bazhin V.
    EUROPEAN JOURNAL OF CANCER, 2015, 51 : S1 - S1
  • [8] REG3β contributes to the immunosuppressive microenvironment of pancreatic cancer
    Folch-Puy, Emma
    ONCOIMMUNOLOGY, 2013, 2 (11):
  • [9] SUMOylation and TIGIT inhibition: a novel immunotherapy combination for pancreatic cancer
    Medina, Jorge R. De la Torre
    Joshi, Utsav
    Narayanan, Jaynath Shankara
    Tiriac, Herve
    Chen, Yuan
    White, Rebekah
    CANCER RESEARCH, 2024, 84 (17)
  • [10] Inhibition of SUMOylation enhances responses to irreversible electroporation in pancreatic cancer
    Erdem, S.
    Narayanan, J. S.
    Worni, M.
    Chen, Y.
    White, R.
    BRITISH JOURNAL OF SURGERY, 2021, 108