Structural determinants of binding of the creatine transporter (creat, SLC6A8) inform the functional annotation of the SLC6 transporters family

被引：0
|
作者：
Colas, Claire [1 ]
机构：
[1] Univ Vienna, Pharmaceut Chem, Vienna, Austria
来源：
BIOPHYSICAL JOURNAL | 2022年 / 121卷 / 03期
关键词：
D O I：
暂无
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
1213-Pos
引用
收藏
页码：250A / 250A
页数：1
相关论文
共 50 条
  • [41] Clinical Characteristics, Developmental Trajectory, and Caregiver Burden of Patients With Creatine Transporter Deficiency (SLC6A8)
    Curie, Aurore
    Lion-Francois, Laurence
    Valayannopoulos, Vassili
    Perreton, Nathalie
    Gavanon, Marie
    Touil, Nathalie
    Brun-Laurisse, Amandine
    Gheurbi, Fahra
    Buchy, Marion
    Halep, Hulya
    Cheillan, David
    Mercier, Catherine
    Brassier, Anais
    Desnous, Beatrice
    Kassai, Behrouz
    De Lonlay, Pascale
    Des Portes, Vincent
    NEUROLOGY, 2024, 102 (08) : e209243
  • [42] A novel SLC6A8 mutation associated with intellectual disabilities in a Chinese family exhibiting creatine transporter deficiency: case report
    Wang, Qin
    Yang, Jingxin
    Liu, Yang
    Li, Xingping
    Luo, Fuwei
    Xie, Jiansheng
    BMC MEDICAL GENETICS, 2018, 19
  • [43] Cognitive deficits and increases in creatine precursors in a brain-specific knockout of the creatine transporter gene Slc6a8
    Udobi, K. C.
    Kokenge, A. N.
    Hautman, E. R.
    Ullio, G.
    Coene, J.
    Williams, M. T.
    Vorhees, C. V.
    Mabondzo, A.
    Skelton, M. R.
    GENES BRAIN AND BEHAVIOR, 2018, 17 (06)
  • [44] Creatine transporter (SLC6A8) knockout mice display an increased capacity for in vitro creatine biosynthesis in skeletal muscle
    Russell, Aaron P.
    Ghobrial, Lobna
    Wright, Craig R.
    Lamon, Severine
    Brown, Erin L.
    Kon, Michihiro
    Skelton, Matthew R.
    Snow, Rodney J.
    FRONTIERS IN PHYSIOLOGY, 2014, 5
  • [45] Down-Regulation of the Na+, Cl- Coupled Creatine Transporter CreaT (SLC6A8) by Glycogen Synthase Kinase GSK3β
    Fezai, Myriam
    Jemaa, Mohamed
    Fakhri, Hajar
    Chen, Hong
    Elsir, Bhaeldin
    Pelzl, Lisann
    Lang, Florian
    CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, 2016, 40 (05) : 1231 - 1238
  • [46] Functional and electrophysiological characterization of four non-truncating mutations responsible for creatine transporter (SLC6A8) deficiency syndrome
    Valayannopoulos, Vassili
    Bakouh, Naziha
    Mazzuca, Michel
    Nonnenmacher, Luc
    Hubert, Laurence
    Makaci, Fatna-Lea
    Chabli, Allel
    Salomons, Gajja S.
    Mellot-Draznieks, Caroline
    Brule, Emilie
    de Lonlay, Pascale
    Toulhoat, Herve
    Munnich, Arnold
    Planelles, Gabrielle
    de Keyzer, Yves
    JOURNAL OF INHERITED METABOLIC DISEASE, 2013, 36 (01) : 103 - 112
  • [47] Creatine transporter (CRT/SLC6A8) acting as a guanidino compound transporter at the blood-cerebrospinal fluid barrier
    Tachikawa, Masanori
    Fujinawa, Jun
    Kasai, Yasuyuki
    Takahashi, Masato
    Terasaki, Tetsuya
    Hosoya, Ken-ichi
    YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 2007, 127 : 149 - 150
  • [48] Efficacy of creatine supplementation in a patient with epilepsy with SLC6A8 gene mutations
    Zhang, Yiqi
    Liu, Xianyun
    Peng, Xi
    EPILEPTIC DISORDERS, 2024, 26 (06) : 879 - 881
  • [49] Intracerebroventricular Delivery of SLC6A8 by Self Complimentary AAV9 Restores Brain Creatine and Reduces Hyperactivity in a Mouse Model of SLC6A8 Deficiency
    Webster, Troy B.
    Binsfeld, Robyn T.
    Tkachyova, Ilona
    Schulze, Andreas
    Walia, Jagdeep S.
    Gray, Steven
    MOLECULAR THERAPY, 2023, 31 (04) : 132 - 132
  • [50] Upregulation and epigenetic modification of the creatine transporter SLC6A8 in non-small cell lung cancer
    Kuempers, Christiane
    Schnepf, Karoline
    Marwitz, Sebastian
    Watermann, Christian
    Scheel, Andreas H.
    Fischer, Rieke N.
    Ammerpohl, Ole
    Perner, Sven
    Droemann, Daniel
    Goldmann, Torsten
    HISTOLOGY AND HISTOPATHOLOGY, 2024, 39 (07) : 867 - 876
12345